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Winthrop University Hospital

Bone & Mineral Metabolism

Considered a major public health threat to an estimated 44 million Americans or 55 percent of people age 50 and older, osteoporosis has been reported in people of all ethnic backgrounds.
  • Osteoporosis leads to bone fragility and increased susceptibility to fractures of the hip, spine and wrist, causing bones to weaken and break from minor falls or simple actions, such as a sneeze.
  • The number of fractures attributed to osteoporosis is expected to rise to over 3 million by 2025.
  • Women comprise an estimated 80 percent of patients with this disease, characterized by low bone mass and structural deterioration of bone tissue.
  • The condition remains under-recognized and under-treated in Caucasian and African American women, and risk is increasing most rapidly among Hispanic women.
  • Bones are metabolically very active, rebuilding bone structure, producing red and white blood cells and producing hormones that can affect other bodily functions and may even play a role in developing diabetes and obesity.
Source: National Osteoporosis Foundation

For decades, Winthrop-University Hospital has been internationally recognized as a leader in osteoporosis research, with supporting grants from many sources, including the National Institutes of Health and the pharmaceutical industry. The Hospital�s bone mineral specialists conduct basic science and clinical bone metabolism studies, examining pathogenic mechanisms responsible for the development of skeletal fragility and osteoporosis.

WUH Researchers� Study:

  • Effects of calcium and estrogen on bone mass and body composition in an ethnically diverse population
  • Use of vitamin D in elderly African-American women.
  • Effects of growth hormone on bone metabolism.
  • Novel approaches towards the treatment of painful osteoporotic vertebral compression fractures.
  • new treatments such as percutaenous lumbar decompression
  • the metabolism and regulation of bone formation and resorption activities via bone histomorphometric and microscopic image analysis
  • the pathogenesis and cellular mechanisms of metabolic bone diseases
  • rodent models of osteoporosis to evaluate the efficacy of hormonal therapy and nutritional supplementation.
  • Effects of green tea�s polyphenols and antioxidatives on bone health

Faculty who study Bone & Mineral Metabolism:

John Aloia, M.D.
Mariano Castro-Magano, M.D.
Jodi Evans, Ph.D.
Mageda Mikhail, MD
Orlando Ortiz, M.D.
Morgan Peltier, Ph.D.
Namji YU, M.D.
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259 First Street | Mineola NY 11501 | 516-663-0333


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