Diabetes, a public health threat of epidemic proportions, does not discriminate. It affects every culture, race, age group and gender. Type 2 diabetes is closely linked to the rapid increase in obesity. It accounts for over 90% of all people with diabetes. Type 1 diabetes affects less than 10% of people with diabetes but typically starts in children and always requires insulin replacement. It is caused by the body�s immune responses wiping out cells that make insulin.
Source: National Diabetes Fact Sheet, 2007
- Nearly 24 million American children and adults � almost eight percent of the population � have some form of diabetes; 57 million are considered pre-diabetic.
- This same pattern of rapid increase in people with diabetes is occurring worldwide.
- In 2006, Diabetes was the seventh leading cause of death.
- Complications include heart disease, stroke, hypertension, blindness, kidney disease, neuropathy and lower-limb amputation.
With its growing reputation for having one of the region�s top Diabetes Research Centers, Winthrop researchers are exploring scientific approaches to enhancing prevention, improving management, advancing treatment and, ultimately, uncovering a cure.
WUH Researchers� Study:
- Methods to prevent the progression of type 1 diabetes in patients with new onset type 1 diabetes
- natural history of type 1 diabetes
- effect of fitness/education intervention in an ethnically diverse school-aged and adolescents New York.
- effects of different treatment modalities on the quality of life of patients with type 1 diabetes.
- effects of insulin�s effect on smooth muscle contraction
- effects of prostaglandins in type 2 Diabetes
- endothelial dysfunction in type 2 diabetes, the pathophysiology of renal disease in obese individuals
- regulation of adipose tissue lipocalin D2 Synthase in obese individuals with and without diabetes
- effects of diabetes on mesenchymal cell function in major vessels
- effects of T1DM and T2DM on brain structure
- effects of hypoglycemia and neurochemistry on brain function
- biomarkers for Alzheimers disease in insulin resistant and T2DM patients
Faculty who study Diabetes:
Siham Accacha, M.D.
Eitan Akirav, Ph.D.
Mariano Castro-Magano, M.D.
Jodi Evans, Ph.D.
Barbara George, EdD
Scott Gorenstein, M.D.
Alan Jacobson, M.D.
Robert Levine, M.D.
Mageda Mikhail, MD
Amrita Nayak, MD
Patricia Patrick, Dr.P.H.
Michael Radin, MD
Louis Ragolia, Ph.D.
Larwrence Shapiro, M.D.
Joshua DeLeon, MD
Kevin Marzo, MD