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Winthrop University Hospital

Leonard R. Krilov, MD

Winthrop Titles/Positions

Chief, Pediatric Infectious Disease; Vice Chairman, Department of Pediatrics

Academic Faculty Appointments

Professor of Pediatrics, SUNY Stony Brook School of Medicine

Address

120 Mineola Blvd Mineola, NY 11501

Phone

516-663-3090

Brief Resume

Leonard R. Krilov, MD, FAAP is presently Chief of Pediatric Infectious Diseases and Vice Chairman of Pediatrics at Winthrop University Hospital in Mineola, NY and Professor of Pediatrics at State University of New York Stony Brook School of Medicine. He received his medical training at Columbia University. He then completed a pediatric internship and residency at Johns Hopkins Hospital in Baltimore, Maryland and a Fellowship in pediatric infectious disease at Children’s Hospital Boston, Massachusetts. He is a fellow of the American Academy of Pediatrics, the Infectious Diseases Society of America, and the Pediatric Infectious Disease Society and an elected member of the Society for Pediatric Research and the American Pediatric Society. He is presently co-chair of the infectious disease committee for AAP Chapter 2, District 2 and past-president of the Nassau Pediatric Society.

Dr. Krilov is a native New Yorker. He has a career-long interest in clinical infectious diseases, respiratory viral infections and vaccine development. He has been involved in many of the RSV prevention trials, influenza and other pediatric vaccine trials. He has authored >100 original articles and book chapters. He is editor for Concise Reviews in Infectious Disease, Pediatric Annals, PREP self assessment, eMedicine and Infectious Disease in Practice. He is a reviewer for a number of pediatric and infectious disease journals including Pediatrics, Journal of Pediatrics and the Pediatric Infectious Disease Journal. Dr. Krilov is an elected member of the Executive Council of the Section on Infectious Disease of the American Academy of Pediatrics.

Description of Research Interests/Activities

I am presently involved in a number of multicenter clinical trials primarily related to pediatric vaccines. I am especially interested in respiratory viral infections (RSV, influenza) and have investigated basic laboratory aspects of inflammatory and immunological responses to RSV infection in vitro.

Areas of Experience

Inflammation
clinical trials

Research Team Members

Ann Mock, RN - Research coordinator Diana Kong, PNP - Research assistant Paul J. Lee, MD - co-investigator

Selected Publications

1. Krilov LR, Weiner LB, Yogev R, et al. The 2009 COID recommendations for RSV prophylaxis: Issues of efficacy, evidence-based medicine. Pediatrics 2009; 124: 1682-4.
2. Krilov LR, Palazzio DL, Fernandes AW, et al. Prevalence of respiratory syncytial (RSV) risk factors and cost implications of immunoprophylaxis to infants 32 to 35 weeks gestation for health plans in the United States. Value in Health 2010; 13:77-86.
3. Krilov LR. Influenza vaccines: The key to disease prevention and control. Pediatr Annals 2009; 38: 650 -654.
4. Duff SB, Scott EA, Mafilios MS, Todd EC, Krilov LR, Geddies AM, Ackerman SH. Cost-effectiveness of a targeted disinfection program in household kitchens to prevent foodborne illnesses in the United States, Canada, and the United Kingdom. Journal of Food Protection. 2003; 11: 2103-2115.
5. Krilov LR, McCloskey TW, Harkness SH, Pontrelli LR, Pahwa S. Alterations in apoptosis of cord and adult peripheral blood mononuclear cells induced by in vitro infection with respiratory syncytial virus. J Infect Dis, 2000; 181: 349-353.
6. Barone SR, Pontrelli LR, Krilov LR. The differentiation of Kawasaki disease, atypical Kawasaki disease and adenoviral infection by the use of clinical features and a rapid adenoviral direct fluorescent antigen test. Arch Pediatr Adolesc Med. 2000; 154: 453-456.
7. Krilov, LR, Fisher M, Friedman SB, Reitman D, Mandel FS. Course and outcome of chronic fatigue in children and adolescents. Pediatrics 1998;102:360-366.
8. Krilov LR, Mandel FS, Barone SR, Fagin JC, and the Bronchiolitis Study Group. Follow-up of children with bronchiolitis in 1986-1987: Potential effect of ribavirin on long-term pulmonary function. Pediatr Inf. Dis J; 1997; 16:273 - 276.
9. Pelcovitz D, Septimus A, Friedman S, Krilov LR, Mandel F, Kaplan S. Psychosocial correlates of chronic fatigue syndrome in adolescent girls. J Devel Behav Pediatrics 1995; 16:333-338.
10. Barone SR, Kaplan MH, Krilov LR, Human Herpes Virus 6 infection in children with first time febrile seizures. Journal of Pediatrics 1995; 127:95-97.
11. Krilov LR, Barone SR, Mandel FS, Cusak TM, Gaber DJ, Rubino JR. Impact of an infection control program in a specialized preschool. Am J Infect Control 1996; 24:167-173.
12. Krilov LR, Harkness SH. Inactivation of respiratory syncytial virus (RSV) by detergents and disinfectants. Pediatr Infectious Disease. 1993; 12:582-584.
13. Krilov LR, Barone SR, Lipson SM, Kaplan MH, Ciamician Z, Harkness SH. Evaluation of a rapid diagnostic test for respiratory syncytial virus (RSV); potential for bedside diagnosis. Pediatrics 1994; 93:903-906.
14. Lipson SM, Krilov LR. Comparison of the rapid second generation Directigen (R) EIA with cell culture and immunofluorescence for the detection of respiratory syncytial virus in nasopharyngeal aspirates. Clinical and Diagnostic Virology. 1994; 2:105-112.
15. Krilov LR, Anderson LJ, Marcoux L, Bonagura VB, Wedgwood JF. Antibody mediated enhancement of respiratory syncytial virus (RSV) infection in two monocyte/macrophage cell lines. J Infect Dis. 1989; 160:777-782.
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