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Rheumatology

Program Director's Message

The NYU Winthrop Hospital-Nassau University Medical Center integrated Rheumatology fellowship strives to produce exceedingly well trained consultants in rheumatic and immunologic disorders. The wide spectrum of pathology seen at NYU Winthrop and our affiliate serves as a foundation for our clinical educational curriculum. Our didactic basic and clinical science curriculum enhances the clinical experience by emphasizing the epidemiology, pathophysiology and immunology of rheumatic diseases as well as evidence based approaches to advanced therapeutics. Dedicated time is provided to pursue clinical, translational and quality improvement research projects with faculty mentors.

Program at a Glance

  • Extensive clinical exposure to a wide range of rheumatic diseases at Winthrop and at a tertiary care county medical facility
  • One-to-one faculty to fellow ratio
  • Experience with immunologic aspects of rheumatic disease through the inclusion of the allergy and immunology service within the Division
  • Opportunity to participate in clinical and bench research, with major areas of investigation in rheumatologic aspects of Sjögren’s Syndrome, large vessel vasculitis and accelerated atherosclerosis in SLE, RA and psoriatic arthritis.
  • MSK Ultrasound experience in Division
  • Rotation in Pediatric Rheumatology
  • Generous house staff benefits, including heavily subsidized housing and three complimentary meals per day

Rheumatoloy Fellowshop at NYU Winthrop

Curriculum

This is a two-year integrated fellowship sponsored by NYU Winthrop Hospital with sites at NYU Winthrop Hospital (NYUWH) and Nassau University Medical Center (NUMC). Each fellow serves as the primary consultant under supervision for inpatients admitted on the Rheumatology Service at both sites. The fellows are responsible for approximately 250 consults over the course of the year at NYU Winthrop. In addition, while on the NUMC Rotation, fellows supervise the management and treatment of inpatients and perform consultations at Nassau University Medical Center. Fellows attend 2 continuity clinics per week at Winthrop, a weekly lupus clinic and arthritis clinic at NUMC where it is expected, that under supervision, they will assume responsibility for all aspects of patient care.

Rheumatoloy Fellowshop at NYU Winthrop

On the Outpatient rotation, the fellows have the opportunity to attend sessions in Orthopedics, MSK Ultrasound in Radiology, Bone Density/DEXA and Pediatric Rheumatology 3 half days per week dependent on their interests. The didactic program includes a weekly Rheumatology, Academic and Research Conference and a weekly Clinical Conference. Journal Club, Quality Improvement Conferences, Basic Science of Medicine Lecture Series and Research Work in Progress Conferences are regularly scheduled throughout the academic year. Clinical and bench research projects are chosen in consultation with the faculty. Musculoskeletal ultrasound teaching sessions are held in the Division weekly.

Rotations in Months

  NYU Winthrop Clinical Service Nassau University Medical Center Clinical Service Research NYU Winthrop Outpatient/Elective
PGY 4 3 3 3 3
PGY 5 3 3 3 3

Clinical Services

The Division of Rheumatology, Allergy & Immunology provides a wide range of consultative and therapeutic services for patients with rheumatic and autoimmune disorders through active inpatient and outpatient services. 

  • Arthritis and Rheumatic Disease Center Program
  • Vasculitis Evaluation and Therapy program
  • Sjögren’s Syndrome program
  • Lupus Clinic (in collaboration with NUMC)
  • Clinical Trials Program

Rheumatoloy Fellowshop at NYU Winthrop

Research

  • Bench Research in collaboration with the NYU Winthrop Research Institute:
    • Accelerated atherosclerosis in SLE and other autoimmune diseases
  • Clinical outcome studies in:
    • Polymyalgia Rheumatica and Giant Cell Arteritis
    • Sjögren’s syndrome
    • Rheumatoid Arthritis

Key Faculty

Steven Carsons, MD, Program Director

  • Professor of Medicine
  • Chief, Division of Rheumatology, Allergy & Immunology. 
  • Fellowship Program Director
  • Director, Clinical and Translational Research, NYU Winthrop Research Institute
  • Research Interests: Clinical aspects of Sjögren’s Syndrome, mechanisms of inflammation in autoimmune disease.

Prachi Anand, MBBS, Site Director NUMC

  • Associate Professor of Medicine
  • Rheumatology Fellowship Site Director
  • Chief, Division of Rheumatology (NUMC)
  • Program Director, Internal Medicine Residency Program (NUMC)
  • Research Interests: Clinical Aspects of Systemic Lupus

Elise Belilos, MD, Associate Program Director

  • Assistant Professor of Medicine
  • Rheumatology Section Head, Division of Rheumatology, Allergy & Immunology
  • Research Interests: Clinical outcomes in Giant Cell Arteritis and Rheumatoid Arthritis, blood vessel inflammation in Giant Cell Arteritis.

Kristina Belostocki, MD

  • Attending Physician, Division of Rheumatology, Allergy & Immunology
  • Research Interests: Early Inflammatory Arthritis

Gary Rosenblum, DO

  • Assistant Professor of Medicine
  • Division of Rheumatology, Allergy & Immunology
  • Research Interests: Clinical Trials, Gout

Christina Mertelsmann-Voss, MD

  • Pediatric Rheumatology

Recent Publications

Brito-Zerón P, Acar-Denizli N, Zeher M, Rasmussen A, Seror R, Theander E, Li X, Baldini C, Gottenberg JE, Danda D, Quartuccio L, Priori R, Hernandez-Molina G, Kruize AA, Valim V, Kvarnstrom M, Sene D, Gerli R, Praprotnik S, Isenberg D, Solans R, Rischmueller M, Kwok SK, Nordmark G, Suzuki Y, Giacomelli R,
Devauchelle-Pensec V, Bombardieri M, Hofauer B, Bootsma H, Brun JG, Fraile G, Carsons SE, Gheita TA, Morel J, Vollenveider C, Atzeni F, Retamozo S, Horvath IF, Sivils K, Mandl T, Sandhya P, De Vita S, Sanchez-Guerrero J, van der Heijden E, Trevisani VFM, Wahren-Herlenius M, Mariette X, Ramos-Casals M; EULAR-SS Task Force Big Data Consortium. Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjögren Project Consortium. Ann Rheum Dis. 2017 Jun;76(6):1042-1050. Epub 2016 Nov 29. PubMed PMID: 27899373.

Carsons SE, Vivino FB, Parke A, Carteron N, Sankar V, Brasington R, Brennan MT, Ehlers W, Fox R, Scofield H, Hammitt KM, Birnbaum J, Kassan S, Mandel S. Treatment Guidelines for Rheumatologic Manifestations of Sjögren's Syndrome: Use of Biologic Agents, Management of Fatigue, and Inflammatory Musculoskeletal Pain. Arthritis Care Res (Hoboken). 2017 Apr;69(4):517-527. Epub 2017 Mar 3. Review. PubMed PMID: 27390247.

Carsons SE, Bhimji SS. Sjogren Syndrome. 2017 Feb 7. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2017 Jun-. Available from http://www.ncbi.nlm.nih.gov/books/NBK431049/
PMID: 28613703.

Voloshyna I, Kasselman LJ, Carsons SE, Littlefield MJ, Gomolin IH, De Leon J, Reiss AB. COX-2-dependent and independent effects of COX-2 inhibitors and NSAIDs on proatherogenic changes in human monocytes/macrophages. J Investig Med. 2017 Mar;65(3):694-704. doi: 10.1136/jim-2016-000259. Epub 2016 Dec 9. PubMed PMID: 27940550.

Mohammed Bari, Anam Shaikh, Valerie Comissiong, Bivin Varghese and Steven E. Carsons. Sjögren’s Syndrome (SS): The Role of Traditional (SS-A/SS-B) and Novel Antibodies in Diagnosis [abstract]. Arthritis Rheumatol. 2016;68 (suppl 10)

Brito-Zeron P, Acar-Denizil N, Zeher M, Rasmussen A, Seror R, Theander E, Li S, Baldini C, Gottenberg JE, Danda D, Quartuccio L, Priori R, Hernandez-Molina G, Fruize AA, Valim V, Kvarnstrom M, Sene DGerli R, Praprotnik S, Isenbert D, Solans R, Rischmueller M, Kwork SK, NOrdmark G, Suzuki Y, Giacomelli R, Devauchelle-Pensec V, Bombadieri M, Hofauer B, Bootsma H, Brun JG, Fraile G, Carsons SE, Gheita TA, Morel J, Vollenveider C, Atzeni F, Retamozo S, Horvath IF, Sivils K, Mandl T, Sandhya P, De Vita S, Canchez-Guerro J, van der Heijden E, Tresvisani VF, Wahren-Herlenius M, Mariette X, Ramos-Casals M; EULAR Task Force Big Data Consortium. Influence of geolocation and ethnicity on the phenotypic expression of primary Sjogren’s syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjogren Project Consortium. An Rheum Dis. 2016 Nov 29. Pii: annrheumdis-2016-209952. Doi:10.1136/annrheumdis-2016-209952 [Epub ahead of print] PMID 27899373

Daniel Jo, Melissa Fazzari, Donald Brand, Steven E. Carsons and Elise Belilos.
Treatment and Outcome of Patients with a Diagnosis of Healed Arteritis on Temporal Artery Biopsy Arthritis Rheumatol. 2016;68 (suppl 10)

Siegart NM, Voloshyna I, De Leon J, Carsons SE, Teboul I, Kasselman, LJ, Mattana J, Reiss AB. Correcting Atherogenic Effects of Lupus Plasma on Macrophages with Resveratrol and Mycophenolate. J Invest Med. 2016.

Voloshyna I, Kasselman L, Carsons S, Littlefield M, Gomolin I, DeLeon J, Reiss A. COX-2 dependent and independent effects of COX-2 inhibitors and NSAIDS on proatherogenic changes in human monocytes/macrophages. J Invest Med 2016. DOI: 10.1136/jim-2016-000259 9 Dec 2016. Funded by Winthrop Research Institute Pilot and Feasibility Grant – Collaboration of clinicians and scientist from multiple divisions

Shiboski CH, Shiboski SC, Seror R, Criswell LA, Latetoulle M, Lietman TM, Rasmussen A, Scofield H, Vitali C, Bowman SJ, Marriette X, International Sjögren’s Syndrome Criteria Working Group. 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome: A consensus and data-driven methodology involving three international patient cohorts. Ann Rheum Dis. 2017 Jan;76(1):9-16. Epub 2016 Oct 26. PMID: 27789466.

Vivino FB, Carsons SE, Foulks G, Daniels TE, Parke A, Brennan MT, Forstot SL, Scofield RH, Hammitt KM. New Treatment Guidelines for Sjogren’s Disease. Rheum Dis Clin North Am 2016 Aug;42(3):531-51 Review PMID 27431353

Carsons S, Vivino F, Parke A, Carteron N, Sankar V, Brasington R, Brennan MT, Ehlers W, Fox R, Scofield H, Hammitt KM, Birnbaum J, Kassan, Mandel S. Treatment Guidelines for Rheumatologic Manifestations of Sjögren’s: Use of Biologics, Management of Fatigue and Inflammatory Musculoskeletal Pain. Arthritis Care Res 2016 Jul 7. [Epub ahead of print]

Voloshyna I, Teboul I, Littlefield MJ, Siegart NM, Turi GK, Fazzari MJ, Carsons SE, DeLeon J, Reiss AB. Resveratrol counters systemic lupus erythematosus- associated atherogenicity by normalizing cholesterol efflux. Exp Biol Med (Maywood). 2016 Aug;241(14):1611-9 PMID 27190277

Dejaco C, Singh YP, Perel P, Hutchings A, Camellino D, Mackie S, Abril A, Bachta A, Balint P, Barraclough K, Bianconi L, Buttgereit F, Carsons S, Ching D, Cid M, Cimmino M, Diamantopoulos A, Docken W, Duftner C, Fashanu B, Gilbert K, Hildreth P, Hollywood J, Jayne D, Lima M, Maharaj A, Mallen C, Martinez-Taboada V, Maz M, Merry S, Miller J, Mori S, Neill L, Nordborg E, Nott J, Padbury H, Pease C, Salvarani C, Schirmer M, Schmidt W, Spiera R. 2015 recommendations for the management of polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative. Tronnier D, Wagner A, Whitlock M, Matteson EL, Dasgupta B.Arthritis Rheumatol. 2015 Oct;67(10):2569-80. doi: 10.1002/art.39333. PMID:26352874

Dejaco C1, Singh YP2, Perel P3, Hutchings A4, Camellino D5, Mackie S6, Abril A7, Bachta A8, Balint P9, Barraclough K10, Bianconi L11, Buttgereit F12, Carsons S13, Ching D14, Cid M15, Cimmino M5, Diamantopoulos A16, Docken W17, Duftner C18, Fashanu B2, Gilbert K19, Hildreth P19, Hollywood J2, Jayne D20, Lima M21, Maharaj A22, Mallen C23, Martinez-Taboada V24, Maz M25, Merry S26, Miller J19, Mori S27, Neill L19, Nordborg E28, Nott J19, Padbury H19, Pease C6, Salvarani C29, Schirmer M18, Schmidt W30, Spiera R31, Tronnier D32, Wagner A33, Whitlock M2, Matteson EL34, Dasgupta B2; European League Against Rheumatism; American College of Rheumatology. 2015 Recommendations for the management of polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative. Ann Rheum Dis. 2015 Oct;74(10):1799-807. doi: 10.1136/annrheumdis-2015-207492. PMID 26359488

Seror R1, Bowman SJ2, Brito-Zeron P3, Theander E4, Bootsma H5, Tzioufas A6, Gottenberg JE7, Ramos-Casals M3, Dörner T8, Ravaud P9, Vitali C10, Mariette X1, Asmussen K1, Jacobsen S1, Bartoloni E1, Gerli R1, Bijlsma JW1, Kruize AA1, Bombardieri S1, Bookman A1, Kallenberg C1, Meiners P1, Brun JG1, Jonsson R1, Caporali R1, Carsons S1, De Vita S1, Del Papa N1, Devauchelle V1, Saraux A1, Fauchais AL1, Sibilia J1, Hachulla E1, Illei G1, Isenberg D1, Jones A1, Manoussakis M1, Mandl T1, Jacobsson L1, Demoulins F1, Montecucco C1, Ng WF1, Nishiyama S1, Omdal R1, Parke A1, Praprotnik S1, Tomsic M1, Price E1, Scofield H1, L Sivils K1, Smolen J1, Laqué RS1, Steinfeld S1, Sutcliffe N1, Sumida T1, Valesini G1, Valim V1, Vivino FB1, Vollenweider C1. EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide. 2015 Feb 20;1(1):e000022. doi: 10.1136/rmdopen-2014-000022. eCollection 2015. Review. PMID 26509054

Carsons SE , Movva S, Ienopoli S. ,Aziz S, Gul M, Calixte R and Brodsky T. Can Extraglandular Manifestations Differentiate Primary Sjögren’s Syndrome from Sjögren’s – Systemic Lupus Erythematosus Overlap Syndrome? 2015 Arthritis Rheumatol. 2015; 67 (suppl 10).

Gul M, Chaudhry AA, Chaudhry AA, Sheikh MA, Carsons S. Atypical presentation of CLIPPERS syndrome: a new entity in the differential diagnosis of central nervous system rheumatologic diseases. J. Clin Rheumatol. 2015 Apr; 21(3):144-8

Mounessa JS, Reiss AB, Carsons SE, Voloshyna I. Comparative Effect of Ustekinumab and Adalimumab on Expression of Leptin and Leptin Receptor in THP-1 Human Macrophages. J Invest Med. 2015; 63(3):579.

Salama M, Voloshyna I, Littlefield MJ, Teboul I, De Leon J, Carsons SE, Mattana J, Reiss AB. Immunosuppressive Drugs Mycophenolate Mofetil and Cyclosporin A: Disparate Effects on Atherogenic Lipid Accumulation in THP-1 Human Macrophages. J Invest Med. 2015; 63(3):570.

Ednalino C, Yip J, Carsons SE. Systematic Review of Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus: Focus on Outcome and Therapy. J Clin Rheumatol. 2015 Sep;21(6):305-10. PMID:26308350

Moosa S, Voloshyna I, Siegart NM, De Leon J, Carsons SE, Kasselman LJ, Littlefield MJ, Reiss AB. The Adenosine A2A Receptor Agonist UK-432,097 Stimulates Anti-Atherogenic Reverse Cholesterol Transport Proteins in THP-1 Human Macrophages. J Invest Med. 2016;

Voloshyna I, Mucci T, Sher J, Fonacier LS, Littlefield MJ, Carsons S, Reiss AB. Plasma IL-33 in atopic patients correlates with pro-inflammatory cytokines and changes cholesterol transport protein expression: a surprising neutral overall impact on atherogenicity. Clin Exp Allergy. 2015 Feb 21. doi.1111/cea.12516 [Epub ahead of print] Oct; 45(10):1554-65 PMID 25703059

Voloshyna I, Mounessa J, Carsons, SE, Reiss AB. Effect of inhibition of interelukin-12/23 by usekinumab on the expression of leptin and leptin receptor in human THP-1 macrophages. Clin Exp Dermatol. 2015 June20 doi:10.1111/ced.12699 [Epub ahead of print] 2016 Apr; 41(3):308-11 PMID 26095599

Movva S, Belilos E, Carsons S. Antiphospholipid Syndrome. Medscape Reference. Updated March 24, 2015. Available at: http://emedicine.medscape.com/article/333221-overview.

Fuertes JN1, Anand P, Haggerty G, Kestenbaum M, Rosenblum GC. The physician-patient working alliance and patient psychological attachment, adherence, outcome expectations, and satisfaction in a sample of rheumatology patients. Behav Med. 2015;41(2):60-8.. Epub 2014 Sep 3. Behav Med. Apr-Jun 2015; 41(2)60-68

Reiss AB, De Leon J, Carsons SE, Mounessa J, Littlefield MJ, and Voloshyna, I. Atheroprotective effects of adalimumab and resveratrol in THP-1 human macrophages: changes in expression of proteins involved in lipid efflux. J Am Coll Cardiol.63 (12); Supplement A2049-A2049, 2014.

Rogers E, Reiss, AB, Carsons, SE, De Leon, J, Voloshyna, I. Impact of lupus plasma on lipid accumulation in THP-1 human macrophages. J Investig Med.62(4):771, 2014.

Mounessa, JS, Voloshyna, I, Littlefield, M, Carsons, SE, and Reiss, AB. Effect of
antirheumatic drugs on cholesterol efflux protein expression in THP-1 human macrophages. J Investig Med. 62(4):768,2014.

Sher, JM, Littlefield, M, Reiss, AB, Carsons, S, Fonacier, LF and Voloshyna, I. Association of serum soluble ST2 and interleukin-33 with pro-inflammatory cytokines: A link between allergic disease and inflammation. J Investig Med.62(4):762-763, 2014.

Wu J, Nazir B, Brand DA, Carsons SE. Omega 3 fatty acids and primary Sjögren’s syndrome: Overview and exploratory investigation. Sjögren’s Syndrome: Symptoms, Treatment Options and Potential Health Complications. 2014 Pp.1-12.

Faustman D, Vivino FB, Carsons SE. Treatment of primary Sjögren’s syndrome with Rituximab. Ann Intern Med (Letter) 2014 Sept:161(5)376-77 PMID 25178574