Pulmonary Research Group
At Winthrop-University Hospital, scientists and specialists at the Pulmonary Research Group are pursuing a better understanding of lung diseases through dedicated, on-going research studies.
Pulmonary disease refers to many disorders affecting the lungs, including asthma, chronic obstructive pulmonary disease (COPD), lung cancer, infections like influenza, pneumonia, tuberculosis, and many other breathing problems such as sleep apnea, pulmonary fibrosis and sarcoidosis. Collectively, lung diseases are the #3 cause of deaths in the United States, causing one in seven annually.
Pulmonary Research Group
Research studies focus on cell development and function, as well as tissue injury, recovery and the role of heredity factors in the overall process. The goal is to prevent lung damage in children and adults in order to enhance the quality of life and improve survival rates.
Winthrop’s pulmonary research is shedding light on of how a popular antioxidant known as superoxide dismutase significantly affects treatment and outcome for premature babies with fragile, undeveloped lungs. Additionally, ongoing clinical investigations into the next generation of therapies for asthma, allergies, COPD, emphysema and lung cancer are devoted to bringing the most effective treatments to patients.
The activities of the pulmonary research group include a broad spectrum of clinical trials examining the benefits of new agents for treating patients with sepsis, asthma, pulmonary embolism, and COPD. At the basic science level, the cardiovascular research group, has been recognized for a) studies to control bacterial colonization in the airways, and b) novel methods to reduce oxidant injury and lung infection using molecular and cellular techniques in combination with tissue culture and experimental models.
Specifically, Winthrop researchers are studying:
- The treatment and mechanisms of bronchiectasis, asthma and COPD
- Respiratory infections, specifically community- acquired pneumonia, nosocomial pneumonia, and healthcare associated pneumonia
- The role of adjunctive aerosolized antibiotics for patients with ventilator associated pneumonia
- The use of serum biomarkers to define the proper duration of antibiotic therapy for patients with lung infiltrates
- Resource utilization in the ICU for patients with severe end-stage disease
- Oxidant injury in premature neonates
For more information about Winthrop’s asthma research efforts, visit Asthma Research Center.
Clinical Trials Center on Long Island
The Winthrop-University Hospital Clinical Trials Center (CTC) was established in 2001 to provide our patients and the surrounding community with the most advanced treatment options. The CTC provides the medical staff at Winthrop with the support services necessary to enhance the quality and effectiveness of their research efforts.
The CTC acts functions as a single point of contact to sponsors for contracts, budgets, and regulatory and patient-recruitment issues. A database of active investigators is available to match investigators with sponsored projects.
Winthrop’s Pulmonary Research Physicians
- Jonathon Ilowite, M.D.
- Louis Ragolia, Ph.D.
- Warren Rosenfeld, M.D.
- Joshua DeLeon, M.D.