A Vibrant Research Program at Winthrop


Vol. 18, No. 2
Summer 2008

  • Compassionate, Cutting-Edge Care Provides Relief to 89-Year-Old Patient

  • Winthrop Elects Three New Members to Board of Directors

  • Two Winthrop-University Hospital Physicians Top New York State Lists for Cardiac Care

  • Phyllis & Nathan J. Mistretta Emergency Diagnostic Imaging Center Dedicated at Winthrop

  • RP-7 "Virtual Doctor" Makes it's Debut at Winthrop

  • Congratulations, Top Docs!

  • A Vibrant Research Program at Winthrop

  • Pediatric Bowel Management Program Addresses Unique Needs of Children

  • International Exchange Program Tours Winthrop

  • 23rd Annual Golf Tournament Raises a Record $430,000 for Emergency Services at Winthrop

  • 11th Annual Opera Night Raises $75,000 for Child Life

  • Charlie's Champions Foundation Shows Continued Support for Cancer Center for Kids

  • Community Members Say Yes to Good Health

  • Senator Schumer Hosts Press Conference at Diabetes Education Center

  • 2nd Annual Black & White Ball Raises $300,000 for Cancer Center for Kids

  • Michael Magro Foundation Supports CCFK's School Re-entry Program

  • Starlight Starbright Children's Foundation Helps Make Wishes Come True

  • Winthrop Receives "Found Money"

  • The Miracle Foundation Makes Third Gift of $50,000 to Cancer Center for Kids

  • Swim Laps Go a Long Way in Support of Pediatrics

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    As part of its mission as a teaching hospital, Winthrop-University Hospital supports and encourages ground-breaking biomedical research by its faculty, residents and fellows.

    By providing opportunities for original research projects, the Hospital affords its trainees a learning environment in which they can develop skills that they will put to use throughout their careers, as they pursue greater scientific and biomedical knowledge. These young researchers are mentored in research processes and methods by approximately 170 full-time medical faculty and a range of other professionals at Winthrop, including Ph.D. researchers, biostatisticians and health outcomes researchers.

    In recognition of the extensive research performed at Winthrop, the Hospital hosted its First Annual House Staff Research Day on May 14, 2008. The event included an extensive exhibit of more than 70 posters that described the results of recent research projects, as well as select oral presentations. The posters represented the scholarly work of Winthrop's residents and fellows whose graduate medical education includes clinical training and research endeavors, some of which focus on basic science and others on clinical studies having the potential to yield improved patient care practices. A number of these posters are now being displayed at national medical meetings.

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    Posters of Distinction awardees Praveena Paruchuri, MD; Veronica Brito, MD; Anthony Tramontano, MD; and Jessica Widmer, DO.
    Opening remarks at the Hospital's First Annual House Staff Research Day were offered by James H. Grendell, MD, Chief of the Division of Gastroenterology, Hepatology and Nutrition at Winthrop, and Chairman of the First Annual Research Day Planning Committee, and John F. Aloia, MD, the Hospital's Chief Academic Officer, and Director of Winthrop's Bone Mineral Research Center.

    Several hundred people representing 20 of the institution's medical education programs participated in Research Day, and among the people viewing the impressive array of posters was Winthrop President and CEO, Daniel P. Walsh.

    "This is what distinguishes a teaching hospital from a community hospital," said Mr. Walsh. "The intellectual energy and spirit of inquiry challenges all of us on a daily basis to advance research and strive for clinical excellence."

    In addition to the research projects carried out in the context of medical education and fellowship training at Winthrop, the Hospital's extensive research program includes the:

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    Bone Mineral Research Center, which focuses on both clinical and basic science aspects of bone metabolism;
    CardioPulmonary Research Institute, where laboratory scientists and physician investigators are pursuing a better understanding of heart and lung diseases through studies of cell development and function;
    Office of Health Outcomes Research, which investigates healthcare and its outcomes at the level of the patient, the clinician, the practice setting, the institution, the community and society as a whole;
    Vascular Biology Institute, where researchers focus on the pathogenic mechanisms responsible for the development of cardiovascular omplications observed in diseases such as diabetes, hypertension and kidney failure; and the
    Winthrop Clinical Trials Center, where physician researchers conduct investigational studies of new drugs and protocols on topics ranging from allergies to urology.

    These programs are administered by the Department of Academic Affairs, and are supported by an Institutional Review Board (IRB), which ensures that all research projects conducted at Winthrop are performed in compliance with applicable regulations, and Winthrop's Office of Sponsored Programs (OSP), which supports researchers in their quest for external funding for research projects.

    The First Annual House Staff Research Day was so successful that, according to Dr. Aloia, "the Second Annual Research Day has already been scheduled - and we have booked twice as much space to accommodate the enormous interest in this important scholarly event."

    For additional information about research at Winthrop, please call (516) 663-2521.

    Prior to Research Day, the Judging Committee selected four research projects for oral presentations at the event. Those honored by this selection included:

    Christine Mullin, MD, Ob/Gyn Resident: "Age-Related Pregnancy Outcomes in Elective Single Embryo Transfers."
    Adam Davis, DO, Internal Medicine Resident: "Long-Term Survival Amongst Octogenarians with Left Ventricular Dysfunction."
    Khalid Ahmad, MD, PediatricPulmonary Fellow: "ROS Production & A549 Cell Viability in Respiratory Viral Infection."
    Jolene Muscat, MD, Ob/Gyn Resident: "SMAD1, Neuropilin-1 and Angiopoietin-2 are Downregulated in IUGR Placenta."

    As visitors walked through the displays, a Judging Committee reviewed the posters and discussed the science behind the work with the presenting trainees. The Judging Committee selected the following four Posters of Distinction:

    Anthony Tramontano, MD, Cardiology Fellow: "Circulating endothelial microparticles are elevated in patients with diabetes mellitus: the role of apoptosis."
    Jessica Widmer, DO, Internal Medicine Resident: "Inappropriate proton pump inhibitor (PPI) use in the acute hospital setting can be reduced."
    Veronica Brito, MD, Internal Medicine Research Fellow: "What drives length of stay in pneumonia patients?"
    Praveena Paruchuri, MD, Internal Medicine Resident: "Percutaneous patent foramen ovale (PFO) closure in prolonged post operative hypoxemia."



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