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Clinical Trials

Title Start Date Principal Name
A multi-center, randomized, double-blind, placebo controlled, parallel group study to assess the safety, tolerability, pharmacokinetics and preliminary efficacy of CFZ533 in patients with primary Sjögren’s syndrome 09/10/2015  Steven Carsons, MD 
A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination with ALT-803 in Patients with BCG-Unresponsive High Grade Non-Muscle Invasive Bladder Cancer (NMIBC)    
A multicenter, Open-Label, Non-Randomized Study to Assess the Tolerability and Safety of a Single, Subcutaneous Administration of Ecallantide in Children and Adolescents with Hereditary Angioedema   Mark Davis-Lorton, MD 
A New Paradigm for Vitamin D Sufficiency: A 6-month, randomized, double blind, placebo-controlled study to investigate vitamin D status in elderly Caucasian women   Jane S. Greensher, RN, MA, CCRC 
A non-interventional, stated preference study to examine patient preferences for tyrosine kinase inhibitor (TKI) treatment attributes among adults with epidermal growth factor receptor positive (EGFR+) metastatic non-small cell lung cancer (NSCLC) 11/01/2017  Jeffrey Schneider, MD 
A Phase 3 Randomized, Double-blind, Multi-center Study of Adjuvant Nivolumab versus Placebo in Subjects with High Risk Invasive Urothelial Carcinoma 02/06/2016  Mary O’Keeffe, MD 
A Phase 3, Open-label, Randomized Study of Nivolumab Combined with Ipilimumab, or with Standard of Care Chemotherapy, versus Standard of Care Chemotherapy in Participants with Previously Untreated Unresectable or Metastatic Urothelial Cancer 11/14/2016  Mary O’Keeffe, MD 
A Phase III, Randomized, Multicenter, Open-Label, Comparative Study to Determine the Efficacy of Durvalumab or Durvalumab and Tremelimumab in Combination With Platinum-Based Chemotherapy for the First-Line Treatment in Patients with Extensive Disease (St 05/18/2017  Jeffrey Schneider, MD 
A Pilot Study of Prostate Cancer-Specific Anxiety in Active Surveillance    
A Prospective, Single Arm, Longitudinal Cohort Study To Assess Biomarkers In Real World Patients With Severe Asthma   Marcella Aquino, MD 
A Randomized Phase 3 Study of AM0010 in Combination with FOLFOX Compared with FOLFOX Alone as Second-line Therapy in Patients with Metastatic Pancreatic Cancer that has Progressed During or Following a First-Line Gemcitabine Containing Regimen 02/28/2017  Alexander Hindenburg, MD 
A Randomized Study of Enzalutamide in Patients with Localized Prostate Cancer Undergoing Active Surveillance (ENACT)    
A Randomized, Double-blind, Double Dummy, Chronic Dosing (56 week) Placebo-controlled, Parallel Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of 3 Doses of Benralizumab (MEDI-563) in Patients with Moderate to Very Severe Chronic   Jonathan Ilowite, MD 
A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Effectiveness of a Nutritional Intervention in Improving the Intestinal Mucosal Health Status in Subjects with Crohn’s Disease (CD) Receiving Anti-TNF Therapy (PIONEER-CD) 06/01/2017  Raluca Vrabie, MD 
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of CCX168 (Avacopan) in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis Treated Concomitantly with Rituximab or Cyclophospha 07/01/2017  Elise Belilos, MD 
A Randomized, Multicenter, Phase 2 Study of DSP- 7888 Dosing Emulsion in Combination with Bevacizumab versus Bevacizumab Alone in Patients with Recurrent or Progressive Glioblastoma following Initial Therapy 03/29/2017  Dr. Paul Duic 
A Randomized, Open-Label, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Avelumab (MSB0010718C) in Combination with and/or Following Chemotherapy in Patients with Previously Untreated Epithelial Ovarian Cancer. Javelin Ovarian 100 01/11/2017  Eva Chalas, MD 
A Study of Intravesical Bacillus Calmette-Guerin (BCG) in Combination with ALT-803 in Patients with BCG-Naïve Non-Muscle Invasive Bladder Cancer (NMIBC)    
A Study of Nivolumab in Combination with Ipilimumab (part 1); and Nivolumab plus Ipilimumab in Combination with Chemotherapy vs. Chemotherapy alone (part 2) as First Line Therapy in stage IV Non-Small Cell Lung Cancer (NSCLC) 06/02/2016  Jeffery Schneider, MD 
ALLIANCE 011502: A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive HER2 Negative Breast Cancer: The ABC Trial 08/01/2017  Nina D’Abreo, MD 
Alliance A011401: Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer: BWEL Breast Cancer Weight Loss Study 08/29/2016  Nina D’Abreo, MD 
Antithrombotic Strategy Variability In ATrial Fibrillation and Obstructive Coronary Disease Revascularized with PCI. (AVIATOR 2 Registry)   Kevin Marzo, MD 
Asthma - Xolair   Luz Sison-Fonacier, MD 
Asthma Study   Marcella Aquino, MD 
Bladder Cancer Quality of Life (QoL) Database    
Breast Milk Protein Intolerance and Maternal Dairy Consumption   Dr. Farrah Lazare, DO 
Bronchiectasis Clinical Research   Jonathan Ilowite, MD 
Can Diet and Physical Activity Modulate Ovarian, Fallopian Tube and Primary Peritoneal Cancer Progression-Free Survival? 06/18/2012  Eva Chalas, MD 
Cardiovascular Inflammation Reduction Trial (CIRT)   Joshua DeLeon, MD 
Complete vs Culprit-only Revascularization to Treat Multi-vessel Disease After Primary PCI for STEMI (COMPLETE)   Srihari Naidu, MD 
Development of an Evidenced-Based Tool for Prediction of Sudden Death in Patients with Non-Ischemic Cardiomyopathy - (NICM Registry)   Juan Gaztanaga, MD 
GOG 274: A Phase III Trial of Adjuvant Chemotherapy as Primary Treatment for Locally Advanced Cervical Cancer Compared to Chemoradiation Alone: The Outback Trial 03/21/2013  Eva Chalas, MD 
GOG0286B: A Randomized Phase II/III Study of Paclitaxel/Carboplatin/Metformin (NSC#91485) versus Paclitaxel/Carboplatin/Placebo as Initial Therapy for Measurable Stage III or IVA, Stage IVB, or Recurrent Endometrial Cancer 10/09/2014  Eva Chalas, MD 
Gout Research Study   Gary Rosenblum, DO 
GraftMaster RX Coronary Stent Graft System (JOSTENT)   Kevin Marzo, MD 
Idiopathic Pulmonary Fibrosis (iPF)   Jonathan Ilowite, MD 
IMPELLA RP® Circulatory Support System   Srihari Naidu, MD 
International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA)   Kevin Marzo, MD 
Investigating and Characterizing the Immune Response to Prostate Cancer Treatment    
Medical research study for people with Moderately to Severely Active Ulcerative Colitis   Raluca Vrabie, MD 
Metformin Prostate Cancer Adjuvant Trial    
Methotrexate and Cholesterol Transport Regulation: Impact of Treatment Regimen in Diabetes and Metabolic Syndrome CIRT Sub-Study   Joshua DeLeon, MD 
NRG-BR003: A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node Negative Triple-Negative Breast Cancer 09/24/2015  Nina D’Abreo, MD 
OBGYN: Chronic Hypertension and Pregnancy (CHAP)   Wendy Kinzler, MD 
ONT-380-206: Phase II Randomized, Double-Blinded, Controlled Study of Tucatinib vs. placebo in combination with Capecitabine and Trastuzumab in Patients with Pretreated Unresectable Locally Advanced or Metastatic HER2+ Breast Carcinoma 05/05/2017  Nina D’Abreo, MD 
Participants needed for a Preeclampsia research study 12/15/2016  Martin Chavez, MD 
PARTNER 3: A Prospective, Randomized, Controlled, Multi-Center Study to Establish the Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients Requiring Aortic Valve Replacement Who Have Severe, Calcific, Symptomatic Aortic   Richard Schwartz, MD 
Patients diagnosed with Acute Hereditary Angioedema   Mark Davis-Lorton, MD 
Patients diagnosed with Pulmonary Artery Hypertension (PAH) are being asked to participate in this clinical research study. 12/15/2016  Shilpa DeSouza 
Pediatric Meningococcal Vaccine   Leonard Krilov, MD 
PPCM (peripartum cardiomyopathy) Registry   Vijayapraveena Paruchuri 
Prader-Willi Syndrome Study   Moris A Angulo, MD 
Primary Progressive Multiple Sclerosis (MS)   Malcolm Gottesman, MD 
Prostate Cancer Quality of Life (QoL) Database    
PROTEGO DF4 Registry   Joseph Germano, DO 
R2222-RSV-1332;A Phase 3, Randomized, Double-blind, Placebo controlled Study Evaluating the Efficacy and Safety of a Human Monoclonal Antibody, REGN2222, for the Prevention of Medically Attended RSV Infection in Preterm Infants   Dr. Leonard R. Krilov, MD 
Rheumatoid Arthritis   Steven Carsons, MD 
S1416: Phase II Randomized Placebo-Controlled Trial of Cisplatin with or without ABT-888 (Veliparib) in Metastatic Triple Negative Breast Cancer and/or BRCA Mutation-Associated Breast Cancer 09/08/2016  Nina D’Abreo, MD 
S1418/BR006: A Randomized, Phase III Trial to Evaluate the Efficacy and Safety of MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer with = 1 cm Residual Invasive Cancer or Positive Lymph Nodes (ypN+) after Neoadjuvan 02/02/2017  Nina D’Abreo, MD 
Safety of Calcium and Vitamin D Supplements at Institute of Medicine Upper Limits Recommendations, A Randomized, Controlled Trial 11/01/2017  John F. Aloia, MD 
SURTAVI: Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement   Richard Schwartz, MD 
Tailored Anti-platelet Initiation to Lesson Outcomes Due to Decreased Clopidogrel Response After Percutaneous Coronary Intervention (TAILOR-PCI)   Kevin Marzo, MD 
Tesaro: A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Niraparib Maintenance Treatment in Patients with Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy   Eva Chalas, MD 
The Euro Observation Research Program, Registry of Pregnancy and Cardiac Disease (ROPAC)   Vijayapraveena Paruchuri 
The Global cVAD (ventricular assist device) Registry   Srihari Naidu, MD 
Treatments Against RA and Effect on FDG-PET/CT (The TARGET Trial) 10/06/2016  Steven Carsons, MD 
Type 2 Diabetes   Mageda Mikhail, MD 
Unilateral Nerve-Sparing Cryoablation for Low-Risk, Clinically Localized, Unilateral Prostate Cancer in Potent Men: A Prospective, Phase II Trial (POTENT-C)    
Volunteers with Osteoarthritis or Rheumatoid Arthritis are needed for a research study   Gary Rosenblum, DO